Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | GFER | P55789 | 1/20 | 1.00 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 1.00 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.59 |
| ▸ | FABP4 | P15090 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CTSV | O60911 | 4/20 | 0.54 |
| ▸ | CTSL | P07711 | 4/20 | 0.54 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29747498 | 1.00 | MAPT (1.00) | MAPTGFERNGLY1MAPK8PTPN1 | |
| SCHEMBL351705 | 0.88 | MAPT (0.79) | MAPTGFERNGLY1MAPK8AKR1C3 | |
| SCHEMBL9172301 | 0.86 | MAPT (0.76) | MAPTGFERNGLY1MAPK8AKR1C3 | |
| SCHEMBL7535147 | 0.86 | MAPT (0.74) | MAPTGFERNGLY1AKR1C3AKR1C2 | |
| Hydrochloric Acid SCHEMBL28298843 | 0.85 | MAPT (0.73) | MAPTGFERNGLY1MAPK8AKR1C3 | |
| Fenamic Acid SCHEMBL7265127 | 0.84 | FABP4 (0.77) | MAPTGFERNGLY1MAPK8AKR1C3 | |
| SCHEMBL11647008 | 0.80 | CDC25B (0.67) | MAPTGFERNGLY1AKR1C3AKR1C2 | |
| SCHEMBL8833788 | 0.80 | MAPT (0.67) | MAPTGFERNGLY1AKR1C3AKR1C2 | |
| SCHEMBL8002116 | 0.80 | MAPT (0.67) | MAPTGFERNGLY1AKR1C3AKR1C2 | |
| SCHEMBL3766360 | 0.80 | MAPT (0.64) | MAPTGFERNGLY1FABP4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5702887-A | BENZ(B)ACRIDINIUM-12-CARBOXYLATE COMPOUNDS | CHIRON DIAGNOSTICS CORPORATION (US) | 1997-12-30 | — | — | US | claimed |
| EP-0617288-B1 | Long emission wavelength chemiluminescent compounds and their use in test assays | NOVARTIS AG (CH) | 2002-05-02 | — | — | EP | disclosed |
| US-5879894-A | DETECTION AND/OR QUANTITATION OF AT LEAST TWO SUBSTANCES IN A TEST SAMPLE; APPLICATION IN CLINICAL DIAGNOSTICS | CHIRON DIAGNOSTICS CORPORATION (US) | 1999-03-09 | — | — | US | disclosed |
| US-5702887-A | BENZ(B)ACRIDINIUM-12-CARBOXYLATE COMPOUNDS | CHIRON DIAGNOSTICS CORPORATION (US) | 1997-12-30 | — | — | US | disclosed |
| US-5395752-A | Detecting emission signals of conjugates of angular or linear four ring or three ring acridinium compounds | CIBA CORNING DIAGNOSTICS CORP. (US) | 1995-03-07 | — | — | US | disclosed |
| WO-1994021823-A1 | LONG EMISSION WAVELENGTH CHEMILUMINESCENT COMPOUNDS AND THEIR USE IN TEST ASSAYS | CIBA CORNING DIAGNOSTICS CORP. (US) | 1994-09-29 | — | — | WO | disclosed |
| EP-0617288-A2 | Long emission wavelength chemiluminescent compounds and their use in test assays | CIBA-GEIGY AG (CH) | 1994-09-28 | — | — | EP | disclosed |