Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.44 |
| ▸ | DHFR | P00374 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 4/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7800613 | 0.85 | TP53 (0.49) | SMN1; SMN2CYP1A2CYP3A4TP53CYP2D6 | |
| SCHEMBL7530975 | 0.85 | CYP1A2 (0.46) | SMN1; SMN2CYP1A2CYP3A4TP53CYP2D6 | |
| SCHEMBL14813096 | 0.82 | GHSR (0.49) | SMN1; SMN2CYP1A2CYP3A4TP53CYP2D6 | |
| SCHEMBL14813094 | 0.80 | CYP1A2 (0.49) | SMN1; SMN2CYP1A2CYP3A4TP53CYP2D6 | |
| SCHEMBL7534201 | 0.75 | CYP1A2 (0.62) | SMN1; SMN2CYP1A2CYP3A4TP53CYP2D6 | |
| SCHEMBL7800614 | 0.74 | GHSR (0.43) | SMN1; SMN2CYP1A2CYP3A4TP53CYP2D6 | |
| SCHEMBL7803412 | 0.73 | TP53 (0.46) | SMN1; SMN2CYP1A2CYP3A4TP53CYP2D6 | |
| SCHEMBL14813234 | 0.72 | CYP1A2 (0.63) | SMN1; SMN2CYP1A2CYP3A4TP53CYP2D6 | |
| Sulfuric Acid SCHEMBL7804578 | 0.69 | TP53 (0.45) | SMN1; SMN2CYP1A2CYP3A4TP53CYP2D6 | |
| SCHEMBL12377461 | 0.68 | CYP1A2 (0.74) | SMN1; SMN2CYP1A2CYP3A4TP53CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839803-B1 | Substituted benzylurea derivatives and medicine containing the same | SS PHARMACEUTICAL CO (JP) | 2002-04-03 | — | — | EP | disclosed |