Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481034 | 0.85 | ALOX5 (0.53) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9035603 | 0.81 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL9027778 | 0.78 | ALOX5 (0.48) | ALOX5PTGS1PTGS2 | |
| SCHEMBL1598547 | 0.78 | ALOX5 (0.51) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9367706 | 0.73 | ALOX5 (0.50) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9038451 | 0.72 | ALOX5 (0.43) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9568568 | 0.72 | ALOX5 (0.43) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7476333 | 0.72 | ALOX5 (0.49) | ALOX5PTGS1PTGS2 | |
| SCHEMBL6748248 | 0.71 | ALOX5 (0.48) | ALOX5PTGS1PTGS2 | |
| SCHEMBL6025207 | 0.71 | ALOX5 (0.56) | ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1250332-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | Abbott Laboratories (US) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001044223-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | ABBOTT LABORATORIES (US) | 2001-06-21 | — | — | WO | disclosed |