Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026012 | 0.85 | ALOX5 (0.47) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7481034 | 0.81 | ALOX5 (0.53) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9367706 | 0.78 | ALOX5 (0.50) | ALOX5PTGS1PTGS2 | |
| SCHEMBL1598547 | 0.75 | ALOX5 (0.51) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9027778 | 0.75 | ALOX5 (0.48) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9210578 | 0.72 | ALOX5 (0.57) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7535259 | 0.71 | ALOX5 (0.46) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9047329 | 0.71 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9029002 | 0.70 | ALOX5 (0.70) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9367698 | 0.69 | ALOX5 (0.47) | ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147565-A1 | Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors | G.D. SEARLE & CO. | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147565-A1 | Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors | ALOX5, ALOX12, ALOX15 | ALOX5 1/4885PTGS1 9/4885PTGS2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.