Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 3/20 | 0.63 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | TK1 | P04183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7534083 | 0.89 | DUT (0.56) | DUTUPP1 | |
| SCHEMBL9353739 | 0.86 | DUT (0.64) | DUTTK1 | |
| SCHEMBL9596714 | 0.85 | DUT (0.63) | DUTUPP1DRD2DRD3 | |
| SCHEMBL9596932 | 0.85 | DUT (0.63) | DUTUPP1DRD2DRD3 | |
| SCHEMBL7535475 | 0.82 | DUT (0.60) | DUTUPP1 | |
| SCHEMBL9354252 | 0.79 | DUT (0.55) | DUTTK1 | |
| SCHEMBL7213472 | 0.76 | UPP1 (0.47) | UPP1TK1 | |
| SCHEMBL9597972 | 0.75 | DUT (0.57) | DUTTK1 | |
| SCHEMBL7541259 | 0.72 | DUT (0.54) | DUT | |
| SCHEMBL8760905 | 0.72 | DUT (0.47) | DUTUPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748316-B1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG IND LTD (KR) | 2002-05-08 | — | — | EP | disclosed |
| US-5889013-A | REACTING AN URACIL COMPOUND WITH N, O-BIS/TRIMETHYLSILYL/ACETAMIDE FOLLOWED BY TETRABUTYLAMMONIUM IODIDE AND CHLOROMETHYL ETHER COMPOUND AND THEN REACTING WITH ARYL SELENOL IN A BASE | SUNKYONG INDUSTRIES CO., INC. (KR) | 1999-03-30 | — | — | US | disclosed |
| EP-0449726-B1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | MITSUBISHI CHEM CORP (JP) | 1997-06-11 | — | — | EP | disclosed |
| EP-0748316-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG INDUSTRIES CO., LTD. (KR) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023138-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG INDUSTRIES CO., LTD. (KR) | 1995-08-31 | — | — | WO | disclosed |
| US-5318972-A | Active against retroviruses, human t-cell leukemia/lymphoma viruses | MITSUBISHI KASEI CORPORATION (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0449726-A1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | Mitsubishi Chemical Corporation (JP) | 1991-10-02 | — | — | EP | disclosed |