Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760119 | 0.90 | DUT (0.43) | DUTTSHRMAPK1NPSR1DHFR | |
| SCHEMBL9353908 | 0.88 | DUT (0.49) | DUTTSHRMAPK1NPSR1ALDH1A1 | |
| SCHEMBL9353726 | 0.87 | DUT (0.48) | DUTTSHRMAPK1NPSR1ALDH1A1 | |
| SCHEMBL9353922 | 0.83 | DUT (0.44) | DUTTSHRMAPK1NPSR1ALDH1A1 | |
| SCHEMBL8760090 | 0.82 | UPP1 (0.49) | TSHRMAPK1NPSR1ALDH1A1UPP1 | |
| SCHEMBL599846 | 0.82 | ALDH1A1 (0.41) | TSHRMAPK1NPSR1ALDH1A1UPP1 | |
| SCHEMBL9597854 | 0.80 | ALDH1A1 (0.53) | TSHRMAPK1NPSR1ALDH1A1UPP1 | |
| SCHEMBL8761019 | 0.79 | DUT (0.46) | DUTMAPK1ALDH1A1UPP1PARP1 | |
| SCHEMBL9357384 | 0.79 | DUT (0.56) | DUTTSHRMAPK1NPSR1ALDH1A1 | |
| SCHEMBL8760114 | 0.78 | DUT (0.49) | DUTNPSR1ALDH1A1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449726-B1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | MITSUBISHI CHEM CORP (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5318972-A | Active against retroviruses, human t-cell leukemia/lymphoma viruses | MITSUBISHI KASEI CORPORATION (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0449726-A1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | Mitsubishi Chemical Corporation (JP) | 1991-10-02 | — | — | EP | disclosed |