Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8816951 | 0.92 | MAOA (0.48) | MAOAMAOBMAPKAPK2GAANPSR1 | |
| SCHEMBL28799893 | 0.83 | MAOA (0.53) | MAOAMAOBMAPKAPK2GAANPSR1 | |
| SCHEMBL9056290 | 0.74 | ACSL1 (0.40) | MAOAMAOBACSL1 | |
| SCHEMBL9057696 | 0.74 | ACSL1 (0.40) | MAOAMAOBACSL1 | |
| SCHEMBL11302124 | 0.73 | MAOA (0.59) | MAOAMAOBMAPKAPK2GAANPSR1 | |
| SCHEMBL8814941 | 0.73 | MAOA (0.59) | MAOAMAOBMAPKAPK2GAANPSR1 | |
| SCHEMBL16975012 | 0.73 | MAOA (0.59) | MAOAMAOBMAPKAPK2GAANPSR1 | |
| SCHEMBL3690493 | 0.73 | MAOA (0.59) | MAOAMAOBMAPKAPK2GAANPSR1 | |
| SCHEMBL14812166 | 0.73 | MAOA (0.59) | MAOAMAOBMAPKAPK2GAANPSR1 | |
| SCHEMBL88260 | 0.73 | MAOA (0.59) | MAOAMAOBMAPKAPK2GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020035138-A1 | Activating Cl- secretion | SOUTHERN RESEARCH INSTITUTE (US) | 2002-03-21 | — | — | US | disclosed |
| EP-1032410-A1 | ACTIVATING C1?- SECRETION | Southern Research Institute (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999020294-A1 | ACTIVATING C1- SECRETION | SOUTHERN RESEARCH INSTITUTE (US) | 1999-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035138-A1 | Activating Cl- secretion | CFTR, CLCN2, CLIC1 | MAOA 2111/4885MAOB 2083/4885MAPKAPK2 1706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.