Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371423 | 0.84 | PARP1 (0.58) | PARP1ACHEHDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL1551882 | 0.83 | FURIN (0.46) | PARP1HDAC8HDAC6HPGDKMT2A | |
| SCHEMBL16955311 | 0.82 | PARP1 (0.56) | PARP1ACHEHDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL10143068 | 0.80 | PARP1 (0.54) | PARP1ACHEHDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL76212 | 0.80 | PARP1 (0.65) | PARP1HDAC8HDAC6SMN1; SMN2HPGD | |
| SCHEMBL610252 | 0.80 | PARP1 (0.54) | PARP1ACHEHDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL29444189 | 0.80 | PARP1 (0.54) | PARP1ACHEHDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL9528530 | 0.80 | PARP1 (0.54) | PARP1ACHEHDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL29639739 | 0.80 | PARP1 (0.65) | PARP1HDAC8HDAC6SMN1; SMN2HPGD | |
| SCHEMBL11787753 | 0.78 | PARP1 (0.52) | PARP1ACHEHDAC8HDAC6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1399632-A | Pyrimidine derivative, process for producing the same, and pharmaceutical containing the same as active ingredient | ONO PHARMACEUTICAL CO (JP) | 2003-02-26 | — | — | CN | claimed |
| EP-1219608-A1 | PYRIMIDINE DERIVATIVES, PROCESS FOR PREPARING THE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-03 | — | — | EP | claimed |
| US-10451967-B2 | Acid- and radical-generating agent and method for generating acid and radical | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2019-10-22 | — | — | US | disclosed |
| US-20160342084-A1 | ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2016-11-24 | — | — | US | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| CN-102822168-A | Method for producing isoxazoline derivatives | SYNGENTA PARTICIPATIONS AG | 2012-12-12 | — | — | CN | disclosed |
| CN-102770419-A | Dihydrofuran derivatives as pesticidal compounds | SYNGENTA PARTICIPATIONS A G | 2012-11-07 | — | — | CN | disclosed |
| CN-102762544-A | Isoxazoline derivatives as insecticides | SYNGENTA PARTICIPATIONS AG | 2012-10-31 | — | — | CN | disclosed |
| CN-102639529-A | Isoxazoline derivative-based pesticidal compounds | SYNGENTA PARTICIPATIONS AG | 2012-08-15 | — | — | CN | disclosed |
| CN-1170528-C | Use of inhibitors of KQT1 channel for the production of medicaments for the treatment of helminth and ectoparasite-related diseases | ���ĵ�˹ҩ��¹�����˾ | 2004-10-13 | — | — | CN | disclosed |
| CN-1399632-A | Pyrimidine derivative, process for producing the same, and pharmaceutical containing the same as active ingredient | ONO PHARMACEUTICAL CO (JP) | 2003-02-26 | — | — | CN | disclosed |
| EP-1219608-A1 | PYRIMIDINE DERIVATIVES, PROCESS FOR PREPARING THE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-1219608-A1 | PYRIMIDINE DERIVATIVES, PROCESS FOR PREPARING THE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-03 | — | — | EP | disclosed |
| CN-1330540-A | Utilization of inhibitors of KQT1 channel in order to produce medicament for treating diseases which are caused by parasitic helminths and actoparasites | AVENTIS PHARMA GMBH (DE) | 2002-01-09 | — | — | CN | disclosed |
| CN-1189830-A | Substituted 1, 3-dioxan-5-ylamino-heterocyclic compounds, method for the production thereof and use thereof as pest control agents | HOECHST SCHERING AGREVO GMBH (DE) | 1998-08-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10451967-B2 | Acid- and radical-generating agent and method for generating acid and radical | CBR1, HAO2, CBR3 | PARP1 1166/4885ACHE 4671/4885HDAC8 3395/4885 |
| US-20160342084-A1 | ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL | CBR1, HAO2, CBR3 | PARP1 1166/4885ACHE 4671/4885HDAC8 3395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.