Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479661 | 0.90 | ALOX5 (0.61) | ALOX5PTGS1 | |
| SCHEMBL7474009 | 0.89 | ALOX5 (0.59) | ALOX5PTGS1 | |
| SCHEMBL7534448 | 0.89 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL7478629 | 0.89 | ALOX5 (0.59) | ALOX5PTGS1 | |
| SCHEMBL7477954 | 0.88 | ALOX5 (0.58) | ALOX5PTGS1 | |
| SCHEMBL7472266 | 0.88 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL7475887 | 0.88 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL9128481 | 0.88 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL9128484 | 0.88 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL9128475 | 0.88 | ALOX5 (0.47) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1250332-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | Abbott Laboratories (US) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001044223-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | ABBOTT LABORATORIES (US) | 2001-06-21 | — | — | WO | disclosed |
| US-5432194-A | Antiallergens, antinflammatory agents | ABBOTT LABORATORIES (US) | 1995-07-11 | — | — | US | disclosed |
| WO-1994026264-A1 | (4-ALKOXYPYRAN-4-YL) SUBSTITUTED ARYLALKYLARYL-, ARYLALKENYLARYL-, AND ARYLALKYNYLARYLUREA INHIBITORS OF 5-LIPOXYGENASE | ABBOTT LABORATORIES (US) | 1994-11-24 | — | — | WO | disclosed |
| US-5346914-A | Antiallergens, antiinflammatory agents | ABBOTT LABORATORIES (US) | 1994-09-13 | — | — | US | disclosed |