SCHEMBL7535407

SCHEMBL7535407

Cc1ccccc1/C(C#N)=N\O

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HSD17B10 Q99714 2/20 0.40
TSHR P16473 2/20 0.39
HPGD P15428 2/20 0.39
POLB P06746 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
HIF1A Q16665 1/20 0.38
TP53 P04637 1/20 0.37
ELANE P08246 1/20 0.35
ACHE P22303 1/20 0.35
ERCC5 P28715 1/20 0.34
FEN1 P39748 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7535412 1.00 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2HSD17B10TSHRHPGD
SCHEMBL30886715 0.98 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2HSD17B10TSHRHPGD
SCHEMBL29203894 0.98 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2HSD17B10TSHRHPGD
SCHEMBL28864428 0.84 TSHR (0.39) SMN1; SMN2TSHRHPGDLMNAMAPT
SCHEMBL8589830 0.81 MEN1 (0.42) ALDH1A1SMN1; SMN2HSD17B10TSHRHPGD
SCHEMBL9231759 0.79 RAB9A (0.37) ALDH1A1SMN1; SMN2TSHRPOLBMAPT
SCHEMBL31454814 0.79 RAB9A (0.37) ALDH1A1SMN1; SMN2TSHRPOLBMAPT
SCHEMBL7536194 0.79 RAB9A (0.37) ALDH1A1SMN1; SMN2TSHRPOLBMAPT
SCHEMBL7536188 0.79 RAB9A (0.37) ALDH1A1SMN1; SMN2TSHRPOLBMAPT
SCHEMBL29203893 0.78 MAPT (0.38) ALDH1A1SMN1; SMN2TSHRHPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362212-B1 POTENT FUNGICIDAL ACTIVITY SHIONOGI & COMPANY, LTD. (JP) 2002-03-26 US disclosed
US-20020032227-A1 Oxime derivative and bactericide containing the same as active ingredient TAKASE AKIRA (JP) 2002-03-14 US disclosed
US-6268312-B1 FUNGICIDES SHIONOGI & CO., LTD. (JP) 2001-07-31 US disclosed
US-6048885-A FUNGICIDES SHIONOGI & CO., LTD. (JP) 2000-04-11 US disclosed
EP-0754684-A1 OXIME DERIVATIVE AND BACTERICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT SHIONOGI & CO., LTD. (JP) 1997-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020032227-A1 Oxime derivative and bactericide containing the same as active ingredient MSMO1, O60361, CBR1 ALDH1A1 1113/4885SMN1; SMN2 2104/4885HSD17B10 99/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.