Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1116407 | 0.84 | MEN1 (0.48) | ALDH1A1LMNACES2CES1 | |
| SCHEMBL4998342 | 0.81 | LMNA (0.54) | TP53F2ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL6921768 | 0.78 | ALDH1A1 (0.49) | TP53F2ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL7037791 | 0.78 | ATM (0.47) | TP53ALDH1A1LMNA | |
| SCHEMBL3010141 | 0.78 | TP53 (0.50) | TP53F2ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL28226986 | 0.78 | TP53 (0.50) | TP53F2ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL20299326 | 0.77 | TSHR (0.52) | TP53F2ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL16753741 | 0.77 | PLG (0.41) | CES2CES1 | |
| SCHEMBL8472108 | 0.77 | SMN1; SMN2 (0.52) | TP53F2ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL6002057 | 0.77 | TBXA2R (0.40) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937063-B1 | ARYLOXYPROPANOLAMINE DERIVATIVES, METHOD OF PREPARATION AND APPLICATIONS THEREOF | VIRBAC SA (FR) | 2002-04-10 | — | — | EP | disclosed |
| EP-0937063-A1 | ARYLOXYPROPANOLAMINE DERIVATIVES, METHOD OF PREPARATION AND APPLICATIONS THEREOF | VIRBAC S.A. (FR) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998020005-A1 | ARYLOXYPROPANOLAMINE DERIVATIVES, METHOD OF PREPARATION AND APPLICATIONS THEREOF | VIRBAC S.A. (FR) | 1998-05-14 | — | — | WO | disclosed |