Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10641788 | 0.90 | MEN1 (0.53) | TTPAKMT2AMEN1PDE4APDE3A | |
| SCHEMBL10636293 | 0.88 | TTPA (0.49) | TTPAKMT2AMEN1PDE4APDE3A | |
| SCHEMBL9631048 | 0.87 | MAPT (0.48) | TTPAKMT2AMEN1MAPTTDP1 | |
| SCHEMBL7487350 | 0.87 | MEN1 (0.52) | TTPAKMT2AMEN1PDE4APDE3A | |
| SCHEMBL9630613 | 0.87 | TTPA (0.48) | TTPAKMT2AMEN1PDE4APDE3A | |
| SCHEMBL9632107 | 0.86 | MAPT (0.60) | TTPAKMT2AMEN1MAPTTDP1 | |
| SCHEMBL6978127 | 0.86 | TTPA (0.47) | TTPAKMT2AMEN1PDE4APDE3A | |
| SCHEMBL10642037 | 0.85 | TTPA (0.47) | TTPAKMT2AMEN1PDE4APDE3A | |
| SCHEMBL7838976 | 0.85 | MEN1 (0.51) | TTPAKMT2AMEN1PDE4APDE3A | |
| SCHEMBL10639032 | 0.85 | KMT2A (0.47) | TTPAKMT2AMEN1PDE4APDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891974-B1 | Process for producing chromans | KURARAY CO (JP) | 2002-04-17 | — | — | EP | disclosed |
| US-6133471-A | Process for producing chromans | KURARAY CO., LTD. (JP) | 2000-10-17 | — | — | US | disclosed |
| US-6130341-A | Process for producing chromans | KURARAY CO., LTD. (JP) | 2000-10-10 | — | — | US | disclosed |
| EP-0916665-A1 | Process for preparing chroman derivatives | LONZA A.G. (CH) | 1999-05-19 | — | — | EP | disclosed |
| EP-0891974-A1 | Process for producing chromans | KURARAY CO., LTD. (JP) | 1999-01-20 | — | — | EP | disclosed |
| EP-0139421-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1988-04-27 | — | — | EP | disclosed |
| US-4572912-A | Thiazolidine derivatives, their preparation and compositions containing them | SANKYO COMPANY LIMITED (JP) | 1986-02-25 | — | — | US | disclosed |
| EP-0139421-A1 | Thiazolidine derivatives, their preparation and compositions containing them | SANKYO COMPANY LIMITED (JP) | 1985-05-02 | — | — | EP | disclosed |