Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | TTPA | P49638 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10639032 | 0.90 | KMT2A (0.47) | MAPTKMT2AMEN1TDP1PPARG | |
| SCHEMBL7536176 | 0.87 | TTPA (0.51) | MAPTKMT2AMEN1TDP1PPARG | |
| SCHEMBL9632107 | 0.86 | MAPT (0.60) | MAPTKMT2AMEN1TDP1PTGS2 | |
| SCHEMBL9630761 | 0.85 | TDP1 (0.48) | MAPTKMT2AMEN1TDP1PPARG | |
| SCHEMBL9075912 | 0.80 | PSEN1 (0.40) | MAPTKMT2AMEN1TDP1PSEN1 | |
| SCHEMBL9632312 | 0.78 | MEN1 (0.49) | MAPTKMT2AMEN1TDP1PPARG | |
| SCHEMBL10639001 | 0.78 | PSEN1 (0.40) | MAPTKMT2AMEN1TDP1PPARG | |
| SCHEMBL10641788 | 0.77 | MEN1 (0.53) | MAPTKMT2AMEN1PSEN1CRHBP | |
| SCHEMBL10636293 | 0.77 | TTPA (0.49) | MAPTKMT2AMEN1TDP1PSEN1 | |
| SCHEMBL9631363 | 0.77 | GABRA5 (0.38) | MAPTKMT2AMEN1TDP1PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |