Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | FCER2 | P06734 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | MMP7 | P09237 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12011595 | 0.75 | NISCH (0.49) | ADRA2AADRA2BADRA2C | |
| SCHEMBL7536749 | 0.74 | HRH4 (0.41) | HRH4 | |
| SCHEMBL7536743 | 0.74 | HRH4 (0.41) | HRH4 | |
| SCHEMBL7430897 | 0.72 | ALDH1A1 (0.59) | MMP1FCER2L3MBTL1 | |
| SCHEMBL7539920 | 0.69 | KMT2A (0.47) | L3MBTL1 | |
| SCHEMBL7539935 | 0.69 | KMT2A (0.47) | L3MBTL1 | |
| SCHEMBL7241843 | 0.68 | CYP1A2 (0.53) | ANPEPRNPEPDNPEPL3MBTL1 | |
| SCHEMBL7241840 | 0.68 | CYP1A2 (0.53) | ANPEPRNPEPDNPEPL3MBTL1 | |
| SCHEMBL7430223 | 0.68 | GAA (0.60) | — | |
| SCHEMBL391686 | 0.67 | CYP1A2 (0.47) | MMP1MMP3MMP7ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416393-A1 | Peptidyl difluorodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |