Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | DRD2 | P14416 | 2/20 | 0.60 |
| ▸ | DRD3 | P35462 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | DPP4 | P27487 | 2/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.49 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12918735 | 0.82 | HRH4 (0.67) | HRH4L3MBTL1DRD2DRD3CA12 | |
| SCHEMBL18071180 | 0.82 | HRH4 (1.00) | HRH4L3MBTL1DRD2DRD3CA12 | |
| SCHEMBL24416092 | 0.81 | HRH4 (0.74) | HRH4L3MBTL1DRD2DRD3CA12 | |
| Ethylene SCHEMBL8547383 | 0.81 | HRH4 (0.68) | HRH4L3MBTL1DRD2DRD3CA12 | |
| SCHEMBL13664683 | 0.79 | HRH4 (0.62) | HRH4L3MBTL1DRD2DRD3CA12 | |
| SCHEMBL933006 | 0.79 | HRH4 (0.70) | HRH4L3MBTL1DRD2DRD3CA12 | |
| SCHEMBL16599230 | 0.77 | HRH4 (0.67) | HRH4L3MBTL1DRD2DRD3CA12 | |
| SCHEMBL29078106 | 0.77 | HDAC6 (0.62) | HRH4L3MBTL1DRD2DRD3CA12 | |
| SCHEMBL30518039 | 0.77 | HDAC6 (0.62) | HRH4L3MBTL1DRD2DRD3CA12 | |
| SCHEMBL3769479 | 0.76 | HRH4 (0.55) | HRH4L3MBTL1DRD2DRD3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020437-A2 | BASIC COMPOUNDS CONTAINING TERTIARY AMIDES WITH ACTIVITY ON TACHYKININ RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MENARINI RICERCHE S.P.A. (IT) | 2002-03-14 | — | — | WO | disclosed |