SCHEMBL753687

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2777643	0.91	LIPG (0.41)	LIPGCNR2LIPCGPR55
	SCHEMBL754205	0.83	LIPG (0.47)	LIPGCNR2LIPCPDE3BPDE3A
	SCHEMBL752850	0.83	LIPG (0.47)	LIPGCNR2LIPCGPR55
	SCHEMBL754547	0.81	LIPG (0.38)	LIPGCNR2PDE3BPDE3AGPR55
	SCHEMBL754111	0.81	LIPG (0.45)	LIPGCNR2LIPCGPR55
	SCHEMBL27844391	0.80	CNR2 (0.39)	GLAPOLBCNR2CNR1PDE3B
	SCHEMBL765523	0.79	CNR2 (0.41)	GLAPOLBCNR2CNR1PDE3B
	SCHEMBL753802	0.78	CNR1 (0.39)	GLAPOLBCNR2CNR1TAAR1
	SCHEMBL753861	0.78	LIPG (0.43)	LIPGCNR2LIPCGPR55
	SCHEMBL755310	0.78	LIPG (0.43)	LIPGCNR2LIPCPDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.