Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.59 |
| ▸ | DRD2 | P14416 | 4/20 | 0.59 |
| ▸ | DRD3 | P35462 | 4/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.55 |
| ▸ | NCF1 | P14598 | 2/20 | 0.55 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27373125 | 0.88 | LMNA (0.59) | DRD4DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL12000243 | 0.85 | DRD4 (0.64) | DRD4DRD2DRD3SIGMAR1KDM4E | |
| SCHEMBL27834649 | 0.84 | NCF1 (0.71) | DRD4DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL23536367 | 0.84 | DRD4 (0.59) | DRD4DRD2DRD3SIGMAR1KDM4E | |
| SCHEMBL2454168 | 0.84 | DRD4 (0.63) | DRD4DRD2DRD3SIGMAR1KDM4E | |
| SCHEMBL29931970 | 0.84 | DRD4 (0.59) | DRD4DRD2DRD3SIGMAR1KDM4E | |
| SCHEMBL14132945 | 0.81 | DRD4 (0.59) | DRD4DRD2DRD3SIGMAR1KDM4E | |
| SCHEMBL2456483 | 0.80 | DRD4 (0.58) | DRD4DRD2DRD3SIGMAR1KDM4E | |
| SCHEMBL14094675 | 0.80 | DRD4 (0.55) | DRD4DRD2DRD3SIGMAR1KDM4E | |
| SCHEMBL415676 | 0.80 | DRD4 (0.55) | DRD4DRD2DRD3SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1205473-A1 | VESAMICOL PIPERAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |