Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7387427 | 0.90 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL7703383 | 0.87 | ALDH1A1 (0.45) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL7381743 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL7376997 | 0.85 | RAB9A (0.44) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL7701186 | 0.84 | ALDH1A1 (0.42) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL7378114 | 0.84 | ALDH1A1 (0.42) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL7385960 | 0.81 | MAPT (0.43) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL4243033 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL4728000 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL4876989 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998055475-A1 | GUANIDINE DERIVIATIVES AS INHIBITORS OF NA+/H+ EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-10 | — | — | WO | disclosed |