Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 6/20 | 0.50 |
| ▸ | KCNJ3 | P48549 | 6/20 | 0.50 |
| ▸ | KCNJ5 | P48544 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 2/20 | 0.50 |
| ▸ | PDE2A | O00408 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.50 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.50 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639723 | 0.87 | ALDH1A1 (0.41) | KCNJ6KCNJ3KCNJ5ALDH1A1L3MBTL1 | |
| SCHEMBL31401177 | 0.85 | APEX1 (0.61) | KCNJ6KCNJ3KCNJ5ALDH1A1L3MBTL1 | |
| SCHEMBL29452139 | 0.85 | APEX1 (0.61) | KCNJ6KCNJ3KCNJ5ALDH1A1L3MBTL1 | |
| SCHEMBL31401329 | 0.81 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL17689083 | 0.81 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1804205 | 0.81 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPK1POLBRECQL | |
| SCHEMBL1802590 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL4639661 | 0.79 | HSD11B1 (0.50) | KCNJ6KCNJ3KCNJ5ALDH1A1KMT2A | |
| SCHEMBL4638471 | 0.79 | MAPK1 (0.40) | ALDH1A1L3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL31401370 | 0.78 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |