Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.30 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5383075 | 0.73 | RAB9A (0.40) | PDE10A | |
| SCHEMBL5377275 | 0.73 | RAB9A (0.39) | PDE10ACYSLTR1 | |
| SCHEMBL7488315 | 0.72 | KDM4E (0.43) | PDE10A | |
| SCHEMBL5382459 | 0.69 | KDM4E (0.40) | CYSLTR1 | |
| SCHEMBL5382011 | 0.67 | KDM4E (0.35) | FFAR1 | |
| SCHEMBL5387609 | 0.66 | KDM4E (0.40) | FFAR1 | |
| SCHEMBL5381841 | 0.59 | KDM4E (0.41) | FFAR1CYSLTR2CYSLTR1 | |
| SCHEMBL6157375 | 0.59 | PPARA (0.53) | FFAR1CYSLTR2CYSLTR1 | |
| SCHEMBL6157371 | 0.59 | PPARA (0.53) | FFAR1CYSLTR2CYSLTR1 | |
| SCHEMBL6157321 | 0.59 | KDM4E (0.51) | PDE10ACYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228067-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGYLCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001038325-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-31 | — | — | WO | disclosed |