Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3191876 | 0.88 | RORC (0.44) | RORCCYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL78803 | 0.85 | NPC1 (0.45) | RORCCYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL29463599 | 0.85 | NPC1 (0.45) | RORCCYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL5447098 | 0.85 | RORC (0.39) | RORCCYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL708739 | 0.84 | RORC (0.40) | RORCCYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL11416372 | 0.83 | RORC (0.37) | RORCCYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL713026 | 0.82 | RORC (0.40) | RORCCYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL29706556 | 0.81 | RORC (0.36) | RORCCYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL6454940 | 0.81 | RORC (0.36) | RORCCYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL29706624 | 0.81 | RORC (0.35) | RORCCYP1A2CYP3A4CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576527-B1 | 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS | CIBA SC HOLDING AG (CH) | 2002-05-22 | — | — | EP | disclosed |
| US-5942626-A | REACTING A 5-HALO-SUBSTITUTED BENZOTRIAZOLE WITH A MERCAPTO COMPOUND IN THE PRESENCE OF A GROUP 1A METAL OR GROUP 2A COMPOUND FORMING 5-THIO-SUBSTITUTED 2H-BENZOTRIAZOLES HAVING ENHANCED ABSORBANCE AT LONGER WAVELENGTHS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-08-24 | — | — | US | disclosed |
| US-5516914-A | Compositions stabilized with 5-thio-substituted benzotriazole UV-absorbers | CIBA-GEIGY CORPORATION (US) | 1996-05-14 | — | — | US | disclosed |
| US-5278314-A | N-Phenol-substituted benzotriazoles | CIBA-GEIGY CORPORATION (US) | 1994-01-11 | — | — | US | disclosed |
| EP-0576527-A1 | 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS | Ciba SC Holding AG (CH) | 1994-01-05 | — | — | EP | disclosed |
| WO-1992014718-A1 | 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS | CIBA-GEIGY AG (CH) | 1992-09-03 | — | — | WO | disclosed |