Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL708739 | 0.96 | RORC (0.40) | RORCNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL3191876 | 0.93 | RORC (0.44) | RORCNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL5804791 | 0.89 | NPC1 (0.43) | RORCNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL29706550 | 0.88 | RORC (0.40) | RORCNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL710416 | 0.88 | RORC (0.40) | RORCNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL712574 | 0.85 | RORC (0.34) | RORCNPC1RAB9A | |
| SCHEMBL78803 | 0.84 | NPC1 (0.45) | RORCNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL29463599 | 0.84 | NPC1 (0.45) | RORCNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL5447098 | 0.83 | RORC (0.39) | RORCNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL7537640 | 0.82 | RORC (0.37) | RORCNPC1RAB9ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247571-B2 | Pyridinium and thiazolium conjugates including polyethylene glycols and methods of using the same | MYCOSOL, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| US-8124626-B2 | Methods of treating inflammations and infections with pyridinium salts | MYCOSOL, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20110053987-A1 | PYRIDINIUM AND THIAZOLIUM CONJUGATES INCLUDING POLYETHYLENE GLYCOLS AND METHODS OF USING THE SAME | MYCOSOL, INC. | 2011-03-03 | — | — | US | disclosed |
| US-7820696-B2 | Compounds and methods for controlling fungi, bacteria and insects | MYCOSOL, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-20100267716-A1 | METHODS OF TREATING INFLAMMATIONS AND INFECTIONS WITH PYRIDINIUM SALTS | KLEIN RICHARD B | 2010-10-21 | — | — | US | disclosed |
| US-7547444-B1 | Methods for controlling fungi and bacteria | MYCOSOL, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-20090137639-A1 | METHODS FOR CONTROLLING FUNGI AND BACTERIA | MYCOSOL, INC. | 2009-05-28 | — | — | US | disclosed |
| EP-1601652-B1 | PYRIDINIUM SALTS, COMPOUNDS AND METHODS OF USE | MYCOSOL INC (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2008088917-A2 | METHODS OF USING PYRIDINIUM AND THIAZOLIUM COMPOUNDS AS REAGENTS, DIAGNOSTIC COMPOUNDS AND THERAPEUTIC AGENTS | MYCOSOL, INC. (US) | 2008-07-24 | — | — | WO | disclosed |
| EP-1830846-A4 | THIAZOLIUM COMPOUNDS AND USES THEREOF | MYCOSOL INC (US) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007056556-A2 | POLYETHYLENE GLYCOL CONJUGATES OF PYRIDINIUM AND THIAZOLIUM COMPOUNDS AND METHODS OF USING THE SAME | MYCOSOL, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2006065942-A2 | THIAZOLIUM COMPOUNDS AND USES THEREOF | MYCOSOL, INC. (US) | 2006-06-22 | — | — | WO | disclosed |
| EP-1601652-A2 | PYRIDINIUM SALTS, COMPOUNDS AND METHODS OF USE | Mycosol, Inc. (US) | 2005-12-07 | — | — | EP | disclosed |
| US-20040235898-A1 | Compounds and methods for controlling fungi, bacteria and insects | MYCOSOL, INC. | 2004-11-25 | — | — | US | disclosed |
| US-20040224984-A1 | Methods of treating inflammations and infections with pyridinium salts | MYCOSOL, INC. | 2004-11-11 | — | — | US | disclosed |
| WO-2004078136-A2 | PYRIDINIUM SALTS, COMPOUNDS AND METHODS OF USE | MYCOSOL, INC. (US) | 2004-09-16 | — | — | WO | disclosed |
| US-5443909-A | Heat sensitive recordin material; substrate, recording layer containing colorless basic dye and protective coatings | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1995-08-22 | — | — | US | disclosed |
| EP-0545442-B1 | Microcapsule containing ultraviolet absorber and heat sensitive recording material using the same | NEW OJI PAPER CO LTD (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5272127-A | Heat sensitive recording material using microcapsules containing ultraviolet absorber | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1993-12-21 | — | — | US | disclosed |
| EP-0545442-A1 | Microcapsule containing ultraviolet absorber and heat sensitive recording material using the same | NEW OJI PAPER CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137639-A1 | METHODS FOR CONTROLLING FUNGI AND BACTERIA | PNPO, BLVRB, DPM1 | RORC 3841/4885NPC1 4376/4885RAB9A 3300/4885 |
| US-20040235898-A1 | Compounds and methods for controlling fungi, bacteria and insects | BLVRB, PNPO, PLPBP | RORC 4211/4885NPC1 3954/4885RAB9A 3091/4885 |
| US-20110053987-A1 | PYRIDINIUM AND THIAZOLIUM CONJUGATES INCLUDING POLYETHYLENE GLYCOLS AND METHODS OF USING THE SAME | PLPBP, PTPMT1, PNPO | RORC 2127/4885NPC1 3813/4885RAB9A 4085/4885 |
| US-20100267716-A1 | METHODS OF TREATING INFLAMMATIONS AND INFECTIONS WITH PYRIDINIUM SALTS | PNPO, PLPBP, TPMT | RORC 245/4885NPC1 3038/4885RAB9A 4725/4885 |
| US-20040224984-A1 | Methods of treating inflammations and infections with pyridinium salts | PNPO, PLPBP, TPMT | RORC 245/4885NPC1 3038/4885RAB9A 4725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.