Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6842000 | 0.80 | MAPT (0.43) | HTTMAPTNPSR1GAAKDM4E | |
| SCHEMBL9185883 | 0.73 | KMT2A (0.56) | HTTMAPTNPSR1LMNAKMT2A | |
| SCHEMBL22463087 | 0.71 | BAZ2B (0.43) | HTTMAPTNPSR1GAAKDM4E | |
| SCHEMBL30939738 | 0.71 | ALDH1A1 (0.47) | HTTMAPTNPSR1GAAKDM4E | |
| SCHEMBL4479590 | 0.71 | ALDH1A1 (0.47) | HTTMAPTNPSR1GAAKDM4E | |
| SCHEMBL7540202 | 0.70 | TDP1 (0.39) | MAPTLMNAKMT2AMEN1POLB | |
| SCHEMBL11015444 | 0.70 | TDP1 (0.53) | HTTMAPTNPSR1GAAKDM4E | |
| SCHEMBL5705174 | 0.69 | KMT2A (0.43) | HTTMAPTNPSR1GAAKDM4E | |
| SCHEMBL27795562 | 0.69 | ALDH1A1 (0.47) | HTTMAPTNPSR1GAAKDM4E | |
| SCHEMBL30002032 | 0.69 | ALDH1A1 (0.47) | HTTMAPTNPSR1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1205473-A1 | VESAMICOL PIPERAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |