Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6478476 | 0.75 | HTR2A (0.44) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL15220550 | 0.73 | TDP1 (0.56) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL7537642 | 0.70 | HTT (0.40) | ALDH1A1MAPTCYP3A4ALOX15HSD17B10 | |
| SCHEMBL11332994 | 0.68 | PNMT (0.50) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL16204105 | 0.68 | TDP1 (0.50) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL11108047 | 0.66 | TDP1 (0.54) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL2056814 | 0.66 | TSHR (0.60) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL10815482 | 0.66 | MAPT (0.47) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL65199 | 0.65 | TDP1 (0.61) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL11551963 | 0.65 | TDP1 (0.59) | TDP1TSHRALDH1A1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1205473-A1 | VESAMICOL PIPERAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |