Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hippuric Acid SCHEMBL7486 | 0.85 | GAA (0.68) | GAAMAPTKDM4EHIF1ASLC22A6 | |
| Hippuric Acid SCHEMBL428479 | 0.85 | GAA (0.68) | GAAMAPTKDM4EHIF1ASLC22A6 | |
| SCHEMBL22030672 | 0.85 | GAA (0.68) | GAAMAPTKDM4EHIF1ASLC22A6 | |
| SCHEMBL9169325 | 0.85 | GAA (0.57) | GAAMAPTKDM4EHIF1ASLC22A6 | |
| Hippuric Acid SCHEMBL11709120 | 0.83 | MAPT (0.66) | GAAMAPTKDM4EHIF1ASLC22A6 | |
| Hippuric Acid SCHEMBL657588 | 0.83 | KDM4E (0.66) | GAAMAPTKDM4EHIF1ASLC22A6 | |
| Hippuric Acid SCHEMBL8165809 | 0.83 | MAPT (0.66) | GAAMAPTKDM4EHIF1ASLC22A6 | |
| Hippuric Acid SCHEMBL21569381 | 0.83 | MAPT (0.66) | GAAMAPTKDM4EHIF1ASLC22A6 | |
| Hippuric Acid SCHEMBL15416338 | 0.83 | MAPT (0.66) | GAAMAPTKDM4EHIF1ASLC22A6 | |
| Hippuric Acid SCHEMBL3448563 | 0.83 | MAPT (0.66) | GAAMAPTKDM4EHIF1ASLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |