Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Hippuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.66 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | PTPRC | P08575 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22030672 | 0.98 | GAA (0.68) | MAPTKDM4EHIF1ASLC22A6SLC22A8 | |
| Hippuric Acid SCHEMBL7486 | 0.98 | GAA (0.68) | MAPTKDM4EHIF1ASLC22A6SLC22A8 | |
| Hippuric Acid SCHEMBL428479 | 0.98 | GAA (0.68) | MAPTKDM4EHIF1ASLC22A6SLC22A8 | |
| Hippuric Acid SCHEMBL8165809 | 0.96 | MAPT (0.66) | MAPTKDM4EHIF1ASLC22A6SLC22A8 | |
| Hippuric Acid SCHEMBL11709120 | 0.96 | MAPT (0.66) | MAPTKDM4EHIF1ASLC22A6SLC22A8 | |
| Hippuric Acid SCHEMBL7398337 | 0.96 | MAPT (0.66) | MAPTKDM4EHIF1ASLC22A6SLC22A8 | |
| Hippuric Acid SCHEMBL657588 | 0.96 | KDM4E (0.66) | MAPTKDM4EHIF1ASLC22A6SLC22A8 | |
| Hippuric Acid SCHEMBL21569381 | 0.96 | MAPT (0.66) | MAPTKDM4EHIF1ASLC22A6SLC22A8 | |
| Hippuric Acid SCHEMBL15416338 | 0.96 | MAPT (0.66) | MAPTKDM4EHIF1ASLC22A6SLC22A8 | |
| Hippuric Acid SCHEMBL11656206 | 0.96 | MAPT (0.66) | MAPTKDM4EHIF1ASLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119799549-A | Lactobacillus plantarum and application thereof in preventing streptococcus mutans infection | 重庆医科大学 | 2025-04-11 | — | — | CN | claimed |
| CN-117025435-A | High stress resistance swine enterococcus hainanensis and application thereof | 湖南农业大学 | 2023-11-10 | — | — | CN | claimed |
| CN-116751699-A | Paecilomyces suis Diels of pig origin with antibacterial effect and application thereof | 湖南农业大学 | 2023-09-15 | — | — | CN | claimed |
| CN-116536196-A | Application of enterococcus gallinarum in degradation of hippuric acid | 浙江工业大学 | 2023-08-04 | — | — | CN | claimed |
| CN-114762801-A | Flexible composite membrane material, preparation method thereof and electrifiable composite membrane coiled material with efficient air purification function | 山东海科创新研究院有限公司 | 2022-07-19 | — | — | CN | claimed |
| CN-110724065-B | Hippurate corrosion-resistant ionic liquid and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2022-04-08 | — | — | CN | claimed |
| CN-114002420-A | Preparation method of composite calibration quality control liquid for urinalysis instrument and urinalysis test paper strip | 吉林省富生医疗器械有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-110724065-A | Hippurate corrosion-resistant ionic liquid and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2020-01-24 | — | — | CN | claimed |
| CN-110607323-A | Agrobacterium tumefaciens-mediated rice genetic transformation method | 四川育良生物科技有限公司 | 2019-12-24 | — | — | CN | claimed |
| CN-105821115-A | Hippurate culture medium and preparation method thereof, ninhydrin reagent and identification method of beta-hemolysis group B streptococcus | 山东鑫科生物科技股份有限公司 | 2016-08-03 | — | — | CN | claimed |
| CN-103801180-B | A kind of air purifier | ATOM BIOSCIENCE AND PHARMACEUTICAL Co.,Ltd. (CN) | 2016-05-25 | — | — | CN | claimed |
| CN-103801180-A | Air purifier | ATOM BIOSCIENCE AND PHARMACEUTICAL CO LTD | 2014-05-21 | — | — | CN | claimed |
| CN-101200755-B | Bacterium identification reagent kit as well as preparation method and uses thereof | UNIV SOUTH CHINA AGRICULT | 2011-06-22 | — | — | CN | claimed |
| CN-101200755-A | Bacterium identification reagent kit as well as preparation method and uses thereof | UNIV SOUTH CHINA AGRICULT (CN) | 2008-06-18 | — | — | CN | claimed |
| CN-100334953-C | Preparation for biological prevention and cure of hot pepper epidemic disease and method for producing the same | UNIV NORTHWEST SCI TECH AGRI (CN) | 2007-09-05 | — | — | CN | claimed |
| CN-1543801-A | Preparation for biological prevention and cure of hot pepper epidemic disease and method for producing the same | ����ũ�ֿƼ���ѧ | 2004-11-10 | — | — | CN | claimed |
| US-5500668-A | INK JET PRINTING | XEROX CORPORATION (US) | 1996-03-19 | — | — | US | claimed |
| EP-0244757-B1 | Novel production process of hyaluronic acid and bacterium strain therefor as well as cosmetic composition containing hyaluronic acid | YAKULT HONSHA KK (JP) | 1994-11-09 | — | — | EP | claimed |
| EP-0329164-B1 | Lactic acid bacteria starter for preparation of silage and agent containing the bacteria in the viable state | CALPIS FOOD IND CO LTD (JP) | 1994-09-28 | — | — | EP | claimed |
| EP-0329164-A2 | Lactic acid bacteria starter for preparation of silage and agent containing the bacteria in the viable state | THE CALPIS FOOD INDUSTRY CO., LTD. (JP) | 1989-08-23 | — | — | EP | claimed |