SCHEMBL7537718

SCHEMBL7537718

CCCCCCCCCCCCCCCCCC(=O)NN1CCCC(C)C1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 2/20 0.54
GNAO1 P09471 2/20 0.54
GNAI1 P63096 2/20 0.54
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
POLB P06746 1/20 0.51
MAPT P10636 1/20 0.51
CNR1 P21554 3/20 0.42
CNR2 P34972 3/20 0.42
FAAH O00519 2/20 0.41
MAPK1 P28482 1/20 0.41
CCR2 P41597 1/20 0.41
HSP90AA1 P07900 1/20 0.41
TRPV1 Q8NER1 4/20 0.41
OPRD1 P41143 1/20 0.41
BCHE P06276 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7532146 0.82 GNAI3 (0.55) GNAI3GNAO1GNAI1MEN1KMT2A
SCHEMBL11215579 0.81 GNAI3 (0.71) GNAI3GNAO1GNAI1MEN1KMT2A
SCHEMBL3871463 0.81 GNAI3 (0.71) GNAI3GNAO1GNAI1MEN1KMT2A
SCHEMBL8588178 0.81 GNAI3 (0.71) GNAI3GNAO1GNAI1MEN1KMT2A
SCHEMBL3868277 0.80 GNAI3 (0.69) GNAI3GNAO1GNAI1MEN1KMT2A
SCHEMBL3974367 0.80 GNAI3 (0.69) GNAI3GNAO1GNAI1MEN1KMT2A
SCHEMBL16010753 0.80 GNAI3 (0.69) GNAI3GNAO1GNAI1MEN1KMT2A
SCHEMBL6582896 0.76 MAPT (0.47) MEN1KMT2APOLBMAPTMAPK1
SCHEMBL8423209 0.75 MEN1 (0.88) GNAI3GNAO1GNAI1MEN1KMT2A
SCHEMBL14879717 0.75 MEN1 (0.88) GNAI3GNAO1GNAI1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0873277-B1 USE OF AMIDES FOR CONTROLLING BIOFOULING USING AMIDES BUCKMAN LABOR INC (US) 2002-05-02 EP claimed
US-6030971-A INHIBITING BACTERIA FROM ADHERING TO A SUBMERGIBLE SURFACE WITHOUT KILLING THE BACTERIA BY TREATING WITH AN N-HETROCYCLIC AMIDE; ANTIFOULING AGENTS; BOATS; DENISTRY; WATER TREATMENT; IMPLANTS BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 2000-02-29 US claimed
EP-0873277-A1 METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING AMIDES BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1998-10-28 EP claimed
WO-1997011910-A1 METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING AMIDES BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1997-04-03 WO claimed
EP-0873277-B1 USE OF AMIDES FOR CONTROLLING BIOFOULING USING AMIDES BUCKMAN LABOR INC (US) 2002-05-02 EP disclosed
US-6030971-A INHIBITING BACTERIA FROM ADHERING TO A SUBMERGIBLE SURFACE WITHOUT KILLING THE BACTERIA BY TREATING WITH AN N-HETROCYCLIC AMIDE; ANTIFOULING AGENTS; BOATS; DENISTRY; WATER TREATMENT; IMPLANTS BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 2000-02-29 US disclosed
EP-0873277-A1 METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING AMIDES BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1998-10-28 EP disclosed
US-5814668-A AMIDE COMPOUNDS AS BACTERICIDES IN WATER BUCKMAN LABORATORIES INTERNATIONAL INC. (US) 1998-09-29 US disclosed
WO-1997011910-A1 METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING AMIDES BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1997-04-03 WO disclosed