SCHEMBL755141

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL753810	0.83	MAPK1 (0.53)	MAPTMAPK1MEN1KMT2AGRM2
	SCHEMBL757225	0.80	P4HTM (0.45)	MAPK1KMT2AGRM2LTA4HLMNA
	SCHEMBL12378242	0.79	MAPT (0.48)	MAPTMAPK1MEN1KMT2AGRM2
	SCHEMBL4585367	0.77	MAPT (0.47)	MAPTMAPK1MEN1KMT2AGRM2
	SCHEMBL5547230	0.77	MAPT (0.41)	MAPTMAPK1MEN1KMT2AGRM2
	SCHEMBL10328696	0.77	CYP4F2 (0.44)	MAPTCYP4F2CYP4A11MAPK1MEN1
	SCHEMBL27606155	0.75	GRM2 (0.46)	CYP4F2CYP4A11MAPK1MEN1KMT2A
	SCHEMBL13850891	0.75	RNASEH1 (0.41)	MAPTGRM2KDM5AKDM5BHSP90AA1
	SCHEMBL755009	0.75	LTA4H (0.40)	MAPTMAPK1MEN1KMT2AGRM2
	SCHEMBL755008	0.75	LTA4H (0.40)	MAPTMAPK1MEN1KMT2AGRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.