Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538234 | 1.00 | L3MBTL1 (0.44) | L3MBTL1HPGDKMT2ATAS1R3TAS1R1 | |
| SCHEMBL7539183 | 0.93 | HPGD (0.47) | L3MBTL1HPGDKMT2ATAS1R3TAS1R1 | |
| SCHEMBL7539182 | 0.93 | HPGD (0.47) | L3MBTL1HPGDKMT2ATAS1R3TAS1R1 | |
| SCHEMBL7538833 | 0.91 | FNTA (0.43) | L3MBTL1HPGDKMT2ATAS1R3TAS1R1 | |
| SCHEMBL7538841 | 0.91 | FNTA (0.43) | L3MBTL1HPGDKMT2ATAS1R3TAS1R1 | |
| SCHEMBL7546269 | 0.89 | FNTA (0.53) | KMT2AHTTPSMB5 | |
| SCHEMBL7546272 | 0.89 | FNTA (0.53) | KMT2AHTTPSMB5 | |
| SCHEMBL7544009 | 0.84 | TAS1R3 (0.52) | TAS1R3TAS1R1ITGB2ICAM1ITGAL | |
| SCHEMBL7542040 | 0.83 | ITGB2 (0.53) | ITGB2ICAM1ITGAL | |
| SCHEMBL7539797 | 0.83 | TAS1R3 (0.51) | TAS1R3TAS1R1ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |