Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23392557 | 0.81 | LMNA (0.55) | SMN1; SMN2MAPTMEN1KMT2ARAB9A | |
| SCHEMBL23392559 | 0.81 | LMNA (0.55) | SMN1; SMN2MAPTMEN1KMT2ARAB9A | |
| SCHEMBL12711610 | 0.81 | LMNA (0.61) | SMN1; SMN2MAPTMEN1KMT2ARAB9A | |
| SCHEMBL7536709 | 0.81 | LMNA (0.61) | SMN1; SMN2MAPTMEN1KMT2ARAB9A | |
| SCHEMBL7531135 | 0.81 | MEN1 (0.64) | SMN1; SMN2MAPTMEN1KMT2ARAB9A | |
| SCHEMBL5068509 | 0.80 | CA1 (0.75) | SMN1; SMN2MAPTNAMPTMEN1KMT2A | |
| SCHEMBL2643331 | 0.80 | CA1 (0.54) | SMN1; SMN2MAPTMEN1KMT2ARAB9A | |
| SCHEMBL2643329 | 0.80 | CA1 (0.54) | SMN1; SMN2MAPTMEN1KMT2ARAB9A | |
| SCHEMBL7196823 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPTMEN1KMT2ARAB9A | |
| SCHEMBL5797412 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |