Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.49 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12711610 | 1.00 | LMNA (0.61) | LMNATDP1ALOX12MAPTPOLB | |
| SCHEMBL23392557 | 0.90 | LMNA (0.55) | LMNATDP1ALOX12MAPTPOLB | |
| SCHEMBL23392559 | 0.90 | LMNA (0.55) | LMNATDP1ALOX12MAPTPOLB | |
| SCHEMBL7536762 | 0.88 | KMT2A (0.66) | LMNATDP1ALOX12MAPTALDH1A1 | |
| SCHEMBL7530445 | 0.85 | NPC1 (0.60) | LMNATDP1ALOX12MAPTALDH1A1 | |
| SCHEMBL7536739 | 0.85 | RAB9A (0.48) | LMNATDP1ALOX12MAPTPOLB | |
| SCHEMBL7533926 | 0.85 | TDP1 (0.67) | LMNATDP1ALOX12MAPTMEN1 | |
| SCHEMBL7531135 | 0.83 | MEN1 (0.64) | LMNATDP1ALOX12MAPTPOLB | |
| SCHEMBL27286584 | 0.82 | MAPT (0.67) | LMNATDP1ALOX12MAPTALDH1A1 | |
| SCHEMBL11718194 | 0.82 | IDO1 (0.48) | LMNATDP1ALOX12MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |