SCHEMBL7538465

SCHEMBL7538465

O=S(=O)(O)c1cc(S(=O)(=O)O)c2ccccc2c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPL P40238 7/20 0.58
CYP1A2 P05177 1/20 0.50
CTRC Q99895 2/20 0.47
PGAM1 P18669 1/20 0.47
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
APP P05067 1/20 0.46
MAPT P10636 1/20 0.46
THRB P10828 1/20 0.46
HPGD P15428 1/20 0.46
ALOX12 P18054 1/20 0.46
SNCA P37840 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CYP2C9 P11712 1/20 0.46
MCL1 Q07820 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TTR P02766 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29576188 0.86 MPL (0.66) MPLCYP1A2CTRCCYP2C9MCL1
SCHEMBL10033898 0.86 MPL (0.60) MPLCTRCMEN1MAPTTHRB
SCHEMBL3066618 0.86 MPL (0.66) MPLCYP1A2CTRCCYP2C9MCL1
Ammonia Solution, Strong SCHEMBL25197168 0.84 MPL (0.58) MPLCTRCMEN1MAPTTHRB
SCHEMBL8421029 0.84 TTR (0.56) MPLCYP1A2CTRCMEN1ALDH1A1
SCHEMBL10891904 0.82 KDM4E (0.51) MPLCYP1A2PGAM1MEN1ALDH1A1
SCHEMBL3440640 0.82 TTR (0.55) MPLCYP1A2PGAM1MEN1ALDH1A1
SCHEMBL1810300 0.82 MPL (0.54) MPLCYP1A2CTRCMEN1ALDH1A1
SCHEMBL7965173 0.82 TTR (0.55) MPLCYP1A2CTRCMEN1ALDH1A1
SCHEMBL13460242 0.82 LMNA (0.55) MPLCYP1A2CTRCMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020142700-A1 BINDING DOMAIN MAPPING AND COMPOUNDS, COMPOSITIONS, COMPLEXES, METHODS, AND KITS RELATED THERETO George Mason Research Foundation, Inc. (US) 2020-07-09 WO disclosed
CN-108472310-A Methods of treating ocular diseases or disorders 加利福尼亚大学董事会 2018-08-31 CN disclosed
CN-101634725-B Blue coloring composition for color filter, color filter and colour display device 东洋油墨制造株式会社 2016-10-05 CN disclosed
CN-102879846-B The manufacture method of colored filter, liquid crystal display cells and colored filter JSR株式会社 2016-07-06 CN disclosed
CN-102789020-B The manufacture method of colored filter, liquid crystal display cells and colored filter JSR株式会社 2016-07-06 CN disclosed
CN-102566269-B Coloured composition, colour filter and display element JSR株式会社 2016-06-15 CN disclosed
CN-102692661-B The manufacture method of colored filter, colored filter and liquid crystal display cells JSR CORP. (JP) 2016-01-06 CN disclosed
CN-102955188-B The manufacture method of colored filter, liquid crystal display cells and colored filter JSR CO., LTD. (JP) 2015-12-09 CN disclosed
CN-102789020-A Color filter sheet, liquid crystal display element and manufacture method for color filter sheet JSR CORP 2012-11-21 CN disclosed
CN-102692661-A Color filter, manufacture method of color filter and LCD JSR CORP 2012-09-26 CN disclosed
US-5104978-A Colorfast chemical resistant dyes for cellulose fibers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-04-14 US disclosed
EP-0400647-A1 Polyazo dye compounds having vinylsulfone type and pyridinium type fiber reactive groups SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-12-05 EP disclosed
EP-0400648-A1 Polyazo dye compounds having plural vinylsulfone type fiber reactive groups in one molecule SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-12-05 EP disclosed
US-4906737-A Azo dye of the pyridone series containing a fluoro-s-triazinyl fibre-reactive group CIBA-GEIGY CORPORATION (US) 1990-03-06 US disclosed
US-4540525-A Method for producing 1-naphthol-4-sulphonic acid SANDOZ LTD. (CH) 1985-09-10 US disclosed
EP-0085025-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1983-08-03 EP disclosed
EP-0078007-A1 Metallised polyazo dyestuffs BASF Aktiengesellschaft (DE) 1983-05-04 EP disclosed
US-4245110-A Polyalkylene oxide-containing urethane polyols with sulphonic acid groups BAYER AKTIENGESELLSCHAFT (DE) 1981-01-13 US disclosed
US-4163675-A CONTAINING NAPHTHALENE DERIVATIVES PILOT INK CO., LTD. (JP) 1979-08-07 US disclosed
US-4146509-A ORGANIC AMMONIUM COMPOUNDS USED AS POLYMERIZATION CATALYSTS BAYER AKTIENGESELLSCHAFT (DE) 1979-03-27 US disclosed