Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | MPL | P40238 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SENP2 | Q9HC62 | 4/20 | 0.49 |
| ▸ | SENP1 | Q9P0U3 | 4/20 | 0.49 |
| ▸ | SUMO2 | P61956 | 3/20 | 0.49 |
| ▸ | SUMO1 | P63165 | 3/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421029 | 0.98 | TTR (0.56) | TTRMPLMEN1ALDH1A1APP | |
| SCHEMBL4456435 | 0.85 | SENP2 (0.56) | TTRMPLMEN1ALDH1A1APP | |
| SCHEMBL3440640 | 0.85 | TTR (0.55) | TTRMPLMEN1ALDH1A1APP | |
| SCHEMBL31222829 | 0.83 | SENP2 (0.58) | TTRMPLMEN1ALDH1A1APP | |
| SCHEMBL1891641 | 0.83 | SENP2 (0.58) | TTRMPLMEN1ALDH1A1APP | |
| SCHEMBL7538465 | 0.82 | MPL (0.58) | TTRMPLMEN1ALDH1A1APP | |
| SCHEMBL6938480 | 0.81 | TTR (0.55) | TTRMPLMEN1ALDH1A1APP | |
| SCHEMBL3066618 | 0.81 | MPL (0.66) | MPLCYP1A2CYP2C9MCL1HSD17B10 | |
| SCHEMBL29576188 | 0.81 | MPL (0.66) | MPLCYP1A2CYP2C9MCL1HSD17B10 | |
| SCHEMBL11882616 | 0.80 | NQO1 (0.45) | TTRMPLMEN1ALDH1A1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274714-B1 | REACTING 1,2-NAPHTHOQUINONE-2-DIAZIDE WITH CHLOROSULFURIC ACID; THEN THIONYL CHLORIDE OR PHOSPHORUS PENTACHLORIDE | TOYO GOSEI KOGYO CO., LTD. (JP) | 2001-08-14 | — | — | US | disclosed |
| CN-1273968-A | Method for preparing 1,2-naphthaqinone-2-diazo-4-sulfonic acid chloride | TOYO SNYTHESIS IND CO LTD (JP) | 2000-11-22 | — | — | CN | disclosed |
| EP-1044964-A2 | Method for producing 1,2-naphthoquinone-2-diazide-4-sulphonyl chloride | Toyo Gosei Kogyo Co., Ltd. (JP) | 2000-10-18 | — | — | EP | disclosed |