Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.39 |
| ▸ | MMP3 | P08254 | 4/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 6/20 | 0.38 |
| ▸ | CTSB | P07858 | 6/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538529 | 1.00 | MMP2 (0.41) | MMP2ITGB1ITGA4MMP3MMP1 | |
| SCHEMBL7540598 | 0.94 | ACE (0.39) | MMP2ITGB1ITGA4MMP3MMP1 | |
| SCHEMBL7540592 | 0.94 | ACE (0.39) | MMP2ITGB1ITGA4MMP3MMP1 | |
| SCHEMBL7538783 | 0.93 | PSMB11 (0.39) | MMP2ITGB1ITGA4MMP3MMP1 | |
| SCHEMBL7538788 | 0.93 | PSMB11 (0.39) | MMP2ITGB1ITGA4MMP3MMP1 | |
| SCHEMBL7548177 | 0.93 | MEN1 (0.43) | MMP2ITGB1ITGA4MMP3MMP1 | |
| SCHEMBL7548182 | 0.93 | MEN1 (0.43) | MMP2ITGB1ITGA4MMP3MMP1 | |
| SCHEMBL7543373 | 0.93 | HDAC3 (0.45) | MMP3MMP1RENPSMB8PSMB5 | |
| SCHEMBL7543377 | 0.93 | HDAC3 (0.45) | MMP3MMP1RENPSMB8PSMB5 | |
| SCHEMBL7539469 | 0.90 | MMP2 (0.38) | MMP2ITGB1ITGA4MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |