Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 9/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | FCER2 | P06734 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 4/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 5/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548182 | 1.00 | MEN1 (0.43) | MEN1KMT2ACTSLMMP1FCER2 | |
| SCHEMBL7540598 | 0.93 | ACE (0.39) | CTSLMMP1MMP2RENITGB1 | |
| SCHEMBL7540592 | 0.93 | ACE (0.39) | CTSLMMP1MMP2RENITGB1 | |
| SCHEMBL7538529 | 0.93 | MMP2 (0.41) | CTSLMMP1MMP2RENITGB1 | |
| SCHEMBL7538534 | 0.93 | MMP2 (0.41) | CTSLMMP1MMP2RENITGB1 | |
| SCHEMBL7538783 | 0.93 | PSMB11 (0.39) | MEN1KMT2ACTSLMMP1MMP2 | |
| SCHEMBL7538788 | 0.93 | PSMB11 (0.39) | MEN1KMT2ACTSLMMP1MMP2 | |
| SCHEMBL7543373 | 0.92 | HDAC3 (0.45) | MMP1RENMMP3ALDH1A1MAPT | |
| SCHEMBL7543377 | 0.92 | HDAC3 (0.45) | MMP1RENMMP3ALDH1A1MAPT | |
| SCHEMBL7541665 | 0.92 | MEN1 (0.46) | MEN1KMT2ACTSLMMP1FCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |