Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538530 | 0.90 | ITGB2 (0.48) | ITGA4ITGB7MAPTTP53SMN1; SMN2 | |
| SCHEMBL7539039 | 0.89 | ITGB2 (0.48) | TACR1SCN9AACEITGA4CTSS | |
| SCHEMBL7547460 | 0.86 | ITGB2 (0.56) | ITGA4ITGB7MAPTTP53SMN1; SMN2 | |
| SCHEMBL7544812 | 0.86 | ITGB2 (0.56) | ITGA4ITGB7MAPTTP53SMN1; SMN2 | |
| SCHEMBL6807195 | 0.86 | KMT2A (0.47) | ITGA4ITGB7ITGB2ICAM1ITGAL | |
| SCHEMBL7540780 | 0.86 | ITGB2 (0.45) | MAPTSMN1; SMN2ITGB2ICAM1ITGAL | |
| SCHEMBL6807437 | 0.86 | ITGA4 (0.41) | ACEITGA4ITGB7MAPTSMN1; SMN2 | |
| SCHEMBL7539842 | 0.85 | ITGB2 (0.51) | ITGA4ITGB7ITGB2ICAM1ITGAL | |
| SCHEMBL7544261 | 0.85 | ITGB2 (0.51) | ITGA4ITGB7ITGB2ICAM1ITGAL | |
| SCHEMBL7538428 | 0.85 | ITGB2 (0.55) | ITGA4ITGB7ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |