Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 3/20 | 0.46 |
| ▸ | ACE | P12821 | 3/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 9/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15139681 | 0.86 | CMA1 (0.49) | CMA1ACEITGB3ITGA2BKLK5 | |
| SCHEMBL19390373 | 0.86 | CMA1 (0.49) | CMA1ACEITGB3ITGA2BKLK5 | |
| SCHEMBL17348400 | 0.83 | FKBP1A (0.45) | CMA1ACEACE2KLK5FKBP1A | |
| SCHEMBL7563228 | 0.83 | ACE (0.56) | CMA1ACEACE2ITGB3ITGA2B | |
| SCHEMBL30483497 | 0.82 | ACE (0.43) | CMA1ACEACE2KLK5FKBP1A | |
| SCHEMBL9608922 | 0.81 | FKBP1A (0.44) | ACEACE2KLK5FKBP1A | |
| SCHEMBL12463881 | 0.81 | CMA1 (0.49) | CMA1ACEITGB3ITGA2BKLK5 | |
| SCHEMBL5898625 | 0.80 | FKBP1A (0.46) | FKBP1A | |
| SCHEMBL7327544 | 0.79 | ACE (0.53) | CMA1ACEACE2BCHEACHE | |
| SCHEMBL8254962 | 0.79 | CTSK (0.50) | ACEITGB3ITGA2BKLK5FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028438-A1 | LIPOPEPTIDES AS ABSORPTION ENHANCERS FOR BIOACTIVE COMPOUNDS | KING'S COLLEGE LONDON (GB) | 2002-04-11 | — | — | WO | claimed |