Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539219 | 1.00 | HDAC1 (0.47) | HDAC1HDAC8HDAC4RENALDH1A1 | |
| SCHEMBL7539223 | 1.00 | HDAC1 (0.47) | HDAC1HDAC8HDAC4RENALDH1A1 | |
| SCHEMBL7541769 | 0.87 | HDAC1 (0.51) | HDAC1HDAC8HDAC4ALDH1A1MEN1 | |
| SCHEMBL7541779 | 0.87 | HDAC1 (0.51) | HDAC1HDAC8HDAC4ALDH1A1MEN1 | |
| SCHEMBL7541773 | 0.87 | HDAC1 (0.51) | HDAC1HDAC8HDAC4ALDH1A1MEN1 | |
| SCHEMBL7587021 | 0.86 | CA12 (0.46) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL7587026 | 0.86 | CA12 (0.46) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL7542675 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ATHRBCYP2C9 | |
| SCHEMBL7542685 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ATHRBCYP2C9 | |
| SCHEMBL7542673 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ATHRBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |