Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541773 | 1.00 | HDAC1 (0.51) | HDAC1ALDH1A1HDAC8HDAC4LIMK2 | |
| SCHEMBL7541769 | 1.00 | HDAC1 (0.51) | HDAC1ALDH1A1HDAC8HDAC4LIMK2 | |
| SCHEMBL7539219 | 0.87 | HDAC1 (0.47) | HDAC1ALDH1A1HDAC8HDAC4LIMK2 | |
| SCHEMBL7539223 | 0.87 | HDAC1 (0.47) | HDAC1ALDH1A1HDAC8HDAC4LIMK2 | |
| SCHEMBL7539220 | 0.87 | HDAC1 (0.47) | HDAC1ALDH1A1HDAC8HDAC4LIMK2 | |
| SCHEMBL7541870 | 0.85 | FOLH1 (0.54) | ACEMMECPA1ACE2MMP3 | |
| SCHEMBL7538785 | 0.85 | FOLH1 (0.54) | ACEMMECPA1ACE2MMP3 | |
| SCHEMBL7540008 | 0.83 | MMP3 (0.50) | ACEMMECPA1ACE2MMP3 | |
| SCHEMBL7538694 | 0.82 | FOLH1 (0.59) | ACEMMECPA1ACE2 | |
| SCHEMBL7546158 | 0.80 | FOLH1 (0.53) | ACEMMECPA1ACE2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |