SCHEMBL7539404

SCHEMBL7539404

CCOC(=O)c1ccc(O[Si](C)(C)C)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.59
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
CA7 P43166 2/20 0.59
CA9 Q16790 2/20 0.59
CA14 Q9ULX7 2/20 0.59
ESR1 P03372 1/20 0.59
ESR2 Q92731 1/20 0.59
LMNA P02545 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP3A4 P08684 1/20 0.58
MAOA P21397 1/20 0.58
STS P08842 1/20 0.57
ALDH1A1 P00352 3/20 0.54
HPGD P15428 4/20 0.51
HTT P42858 2/20 0.51
TDP1 Q9NUW8 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
PRSS1 P07477 1/20 0.49
ACR P10323 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7538855 0.86 ALDH1A1 (0.62) ESR1LMNACYP1A2CYP3A4STS
SCHEMBL7546431 0.85 ESR1 (0.66) ESR1LMNACYP1A2CYP3A4STS
SCHEMBL7308998 0.83 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL87450 0.82 CA1 (0.83) CA12CA1CA2CA7CA9
SCHEMBL3096964 0.81 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL8656770 0.81 CA12 (0.68) CA12CA1CA2CA7CA9
SCHEMBL11769771 0.81 CA1 (0.73) CA12CA1CA2CA7CA9
SCHEMBL30271267 0.80 CA1 (0.79) CA12CA1CA2CA7CA9
SCHEMBL21440358 0.80 CA1 (0.79) CA12CA1CA2CA7CA9
SCHEMBL29504635 0.80 CA1 (0.79) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1205482-A2 Alkyl trimethylsiloxybenzoat compounds and method of preparation Clariant Life Science Molecules (Florida) Inc. (US) 2002-05-15 EP disclosed