Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.57 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | IGF1R | P08069 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nicarbazin SCHEMBL578675 | 0.95 | MEN1 (0.66) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL8371944 | 0.95 | MEN1 (0.66) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL11055960 | 0.83 | MEN1 (0.85) | NPC1RAB9AMEN1KMT2ACXCR1 | |
| Diphenylurea SCHEMBL27302793 | 0.82 | MEN1 (0.81) | NPC1RAB9AMEN1KMT2ACXCR1 | |
| SCHEMBL23069044 | 0.77 | MEN1 (0.73) | NPC1RAB9AMEN1KMT2ACXCR1 | |
| SCHEMBL6302157 | 0.77 | MEN1 (1.00) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL1177730 | 0.77 | MEN1 (1.00) | NPC1RAB9AMEN1KMT2ALMNA | |
| Nicarbazin SCHEMBL578676 | 0.76 | NPC1 (0.60) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL4115432 | 0.76 | MEN1 (0.82) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL11832409 | 0.75 | MEN1 (0.88) | NPC1RAB9AMEN1KMT2ACXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002032426-A1 | FURTHER IMPROVEMENTS IN AND RELATING TO THE CONTROL OF COCCIDIA | BOMAC RESEARCH LIMITED (NZ) | 2002-04-25 | — | — | WO | disclosed |