Nicarbazin

Nicarbazin

SCHEMBL578676

Cc1cc(C)[nH]c(=O)n1.O=C(Nc1ccc([N+](=O)[O-])cc1)Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 5/20 0.60
▸ RAB9A P51151 5/20 0.60
▸ MEN1 O00255 11/20 0.58
▸ KMT2A Q03164 11/20 0.58
▸ MAPT P10636 8/20 0.58
▸ APEX1 P27695 1/20 0.58
▸ MAPK1 P28482 4/20 0.52
▸ LMNA P02545 2/20 0.52
▸ SMN1; SMN2 Q16637 2/20 0.52
▸ NPSR1 Q6W5P4 2/20 0.50
▸ MYOC Q99972 2/20 0.50
▸ POLB P06746 4/20 0.49
▸ TDP1 Q9NUW8 1/20 0.49
▸ TP53 P04637 1/20 0.48
▸ PABPC1 P11940 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nicarbazin SCHEMBL578675 0.80 MEN1 (0.66) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL8371944 0.80 MEN1 (0.66) NPC1RAB9AMEN1KMT2AMAPT
Diphenylurea SCHEMBL7539414 0.76 NPC1 (0.62) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL1177730 0.76 MEN1 (1.00) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL6302157 0.76 MEN1 (1.00) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL4115432 0.75 MEN1 (0.82) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL24430196 0.74 KMT2A (1.00) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL6302417 0.71 MEN1 (0.89) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL6302158 0.70 MEN1 (0.68) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL3460442 0.70 MEN1 (0.79) NPC1RAB9AMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119361720-B Catalyst and preparation method and application thereof 东风汽车集团股份有限公司 2026-05-22 — — CN claimed
US-12606923-B2 Acid-free pyrolytic synthesis of M-N-C catalyst THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-04-21 — — US claimed
CN-119970999-A High-activity anticoccidial nicarbazin composition and preparation method thereof 郑州福源动物药业有限公司 2025-05-13 — — CN claimed
CN-116474816-B Fe-N-C ultralow-temperature SCR denitration catalyst and preparation method and application thereof 山西大学 2025-05-02 — — CN claimed
CN-115501273-B Application of traditional Chinese medicine compound effective extract in preparation of medicine for resisting eimeria tenella 广西大学 2025-03-25 — — CN claimed
CN-119510631-A Method for detecting anticoccidial drug in poultry products by liquid-mass spectrometry 东营市疾病预防控制中心 2025-02-25 — — CN claimed
CN-119361720-A Catalyst and preparation method and application thereof 东风汽车集团股份有限公司 2025-01-24 — — CN claimed
US-12201666-B2 Combination, composition, and method of administering the combination or composition to animals PHIBRO ANIMAL HEALTH CORPORATION (US) 2025-01-21 — — US claimed
CN-118873624-A Veterinary medicine for preventing and treating chicken coccidiosis and preparation method thereof 重庆市畜牧科学院 2024-11-01 — — CN claimed
EP-4440329-A1 RAW-FIBER CRUSTED PELLETS, FEEDSTUFF CONTAINING THEM, AND CORRESPONDING METHODS AND USES Farmerscent GmbH (DE) 2024-10-09 — — EP claimed
US-4665100-A REDUCTION OF CARRYOVER TO SUBSEQUENT LOTS ELI LILLY AND COMPANY (US) 1987-05-12 — — US claimed
EP-0217631-A2 Nicarbazin feed premix ELI LILLY AND COMPANY (US) 1987-04-08 — — EP claimed
EP-0209971-A1 Polyether antibiotic and process for its production ELI LILLY AND COMPANY (US) 1987-01-28 — — EP claimed
EP-0184291-A2 Polyether antibiotic A80190 ELI LILLY AND COMPANY (US) 1986-06-11 — — EP claimed
EP-0182117-A1 Anticoccidial compostions AMERICAN CYANAMID COMPANY (US) 1986-05-28 — — EP claimed
US-4582822-A ANIMAL FEED ADDITIVES ELI LILLY AND COMPANY (US) 1986-04-15 — — US claimed
EP-0015110-B1 ANTICOCCIDIAL COMPOSITION, CARBANILIDES AND METHOD OF PREPARING THEM ELI LILLY AND COMPANY (US) 1985-08-21 — — EP claimed
EP-0060680-A1 Process for formulating a medicated animal feed premix ELI LILLY AND COMPANY (US) 1982-09-22 — — EP claimed
EP-0015110-A2 Anticoccidial composition, carbanilides and method of preparing them ELI LILLY AND COMPANY (US) 1980-09-03 — — EP claimed
US-4218438-A POULTRY FEED ELI LILLY AND COMPANY (US) 1980-08-19 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606923-B2 Acid-free pyrolytic synthesis of M-N-C catalyst LMNA, MNS1, FLNB NPC1 1418/4885RAB9A 1022/4885MEN1 12/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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