Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324555 | 0.85 | HTR1A (0.35) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL7360417 | 0.79 | PREP (0.39) | PREPACHE | |
| SCHEMBL7318862 | 0.76 | PREP (0.43) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL7490329 | 0.75 | — | — | |
| SCHEMBL7350647 | 0.73 | PREP (0.39) | PREP | |
| SCHEMBL7488919 | 0.72 | — | — | |
| SCHEMBL7355169 | 0.71 | PREP (0.51) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL7354558 | 0.69 | PREP (0.41) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL7325883 | 0.66 | PREP (0.49) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL737837 | 0.65 | HTR1A (0.54) | HTR1AHTR2AHTR7DRD3HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |