Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 5/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041143 | 0.77 | ESR1 (0.45) | ESR1LMNATDP1 | |
| SCHEMBL23040641 | 0.74 | ESR1 (0.42) | ESR1LMNATDP1 | |
| SCHEMBL30362784 | 0.71 | CES2 (0.47) | LMNAGAATDP1 | |
| SCHEMBL7511703 | 0.70 | ESR1 (0.58) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL2216124 | 0.68 | NSD2 (0.50) | NSD2ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL24266561 | 0.68 | NSD2 (0.55) | NSD2ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL9451362 | 0.67 | L3MBTL1 (0.39) | L3MBTL1KDM4EPOLBGAA | |
| SCHEMBL4733375 | 0.67 | L3MBTL1 (0.59) | NSD2L3MBTL1SERPINE1TYRKDM4E | |
| SCHEMBL4784772 | 0.67 | L3MBTL1 (0.56) | NSD2ESR1L3MBTL1SERPINE1TYR | |
| SCHEMBL2495353 | 0.67 | NSD2 (1.00) | NSD2L3MBTL1SERPINE1TYRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1205525-A1 | WATER LEAKAGE PREVENTIVE AGENT, WATER LEAKAGE PREVENTIVE MATERIAL MADE WITH THE SAME, AND METHOD OF PREVENTING WATER LEAKAGE | Nippon Kayaku Kabushiki Kaisha (JP) | 2002-05-15 | — | — | EP | disclosed |