Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540036 | 1.00 | MEN1 (0.39) | MEN1KMT2AALDH1A1MAPTACE | |
| SCHEMBL7543387 | 0.94 | MMP2 (0.40) | MEN1KMT2AALDH1A1MAPTCTSL | |
| SCHEMBL7543392 | 0.94 | MMP2 (0.40) | MEN1KMT2AALDH1A1MAPTCTSL | |
| SCHEMBL7539469 | 0.93 | MMP2 (0.38) | MEN1KMT2AALDH1A1MAPTCTSL | |
| SCHEMBL7539472 | 0.93 | MMP2 (0.38) | MEN1KMT2AALDH1A1MAPTCTSL | |
| SCHEMBL7540417 | 0.93 | CTSL (0.37) | MAPTACECTSLITGB1ITGA4 | |
| SCHEMBL7540421 | 0.93 | CTSL (0.37) | MAPTACECTSLITGB1ITGA4 | |
| SCHEMBL7544791 | 0.92 | MEN1 (0.39) | MEN1KMT2AALDH1A1MAPTACE | |
| SCHEMBL7544796 | 0.92 | MEN1 (0.39) | MEN1KMT2AALDH1A1MAPTACE | |
| SCHEMBL7539871 | 0.92 | GRN (0.39) | MEN1KMT2AALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |