Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545670 | 1.00 | ANPEP (0.46) | ANPEPACEMAPK1RAB9AMEN1 | |
| SCHEMBL7544141 | 0.92 | GAA (0.40) | ACEMAPK1RAB9AFPR2GAA | |
| SCHEMBL7542063 | 0.92 | GAA (0.40) | ACEMAPK1RAB9AFPR2GAA | |
| SCHEMBL7538838 | 0.91 | FPR2 (0.38) | ANPEPACERAB9AFPR2LMNA | |
| SCHEMBL7541658 | 0.91 | FPR2 (0.38) | ANPEPACERAB9AFPR2LMNA | |
| SCHEMBL7539858 | 0.91 | ACE (0.39) | ACEMAPK1FPR2LMNASMN1; SMN2 | |
| SCHEMBL7545839 | 0.91 | ACE (0.39) | ACEMAPK1FPR2LMNASMN1; SMN2 | |
| SCHEMBL7542841 | 0.90 | ACE (0.40) | ACEMAPK1FPR2LMNAATM | |
| SCHEMBL7539439 | 0.90 | ANPEP (0.50) | ANPEPRAB9AMEN1KMT2AFPR2 | |
| SCHEMBL7563255 | 0.90 | ACE (0.38) | ANPEPACEMAPK1FPR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |