Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7542063 | 1.00 | GAA (0.40) | GAAMAPTHPGDRAB9AFPR2 | |
| SCHEMBL7539858 | 0.94 | ACE (0.39) | MAPTFPR2SMN1; SMN2ACEMAPK1 | |
| SCHEMBL7538838 | 0.94 | FPR2 (0.38) | GAAMAPTHPGDRAB9AFPR2 | |
| SCHEMBL7545839 | 0.94 | ACE (0.39) | MAPTFPR2SMN1; SMN2ACEMAPK1 | |
| SCHEMBL7541658 | 0.94 | FPR2 (0.38) | GAAMAPTHPGDRAB9AFPR2 | |
| SCHEMBL7538354 | 0.93 | GAA (0.41) | GAAMAPTHPGDRAB9AHDAC3 | |
| SCHEMBL7542841 | 0.93 | ACE (0.40) | FPR2ACEMAPK1 | |
| SCHEMBL7540040 | 0.92 | ANPEP (0.46) | GAARAB9AFPR2SMN1; SMN2ACE | |
| SCHEMBL7545670 | 0.92 | ANPEP (0.46) | GAARAB9AFPR2SMN1; SMN2ACE | |
| SCHEMBL7539014 | 0.91 | HDAC3 (0.39) | GAAMAPTHPGDRAB9AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |