Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.81 |
| ▸ | BRD2 | P25440 | 1/20 | 0.81 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | INMT | O95050 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylpyrrolidone SCHEMBL6590411 | 0.93 | BRD4 (0.77) | BRD4BRD2PIK3CDINMTLMNA | |
| Methylpyrrolidone SCHEMBL3306767 | 0.92 | BRD4 (0.68) | BRD4BRD2PIK3CDINMTLMNA | |
| Methylpyrrolidone SCHEMBL5423326 | 0.90 | — | — | |
| Methylpyrrolidone SCHEMBL487 | 0.90 | — | — | |
| Methylpyrrolidone SCHEMBL1255511 | 0.90 | BRD4 (1.00) | BRD4BRD2PIK3CDINMTLMNA | |
| Methylpyrrolidone SCHEMBL8055062 | 0.90 | BRD4 (1.00) | BRD4BRD2PIK3CDINMTLMNA | |
| Methylpyrrolidone SCHEMBL28183883 | 0.88 | — | — | |
| Methylpyrrolidone SCHEMBL9634127 | 0.88 | — | — | |
| Methylpyrrolidone SCHEMBL27899870 | 0.88 | BRD4 (0.85) | BRD4BRD2PIK3CDINMTLMNA | |
| Methylpyrrolidone SCHEMBL10902634 | 0.88 | BRD4 (0.85) | BRD4BRD2PIK3CDINMTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10414766-B2 | Polymorph of Riociguat and its process for the preparation | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2019-09-17 | — | — | US | claimed |
| US-20190002461-A1 | NOVEL POLYMORPH OF RIOCIGUAT AND ITS PROCESS FOR THE PREPARATION | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2019-01-03 | — | — | US | claimed |
| WO-2017103760-A1 | NOVEL POLYMORPH OF RIOCIGUAT AND ITS PROCESS FOR THE PREPARATION | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2017-06-22 | — | — | WO | claimed |
| US-20130123499-A1 | Method for Purifying a Fused Pyrrolocarbazole Derivative | CEPHALON FRANCE (FR) | 2013-05-16 | — | — | US | claimed |
| JP-11035705-A | — | — | None | — | — | JP | disclosed |
| CN-113804737-B | Polyaniline loaded silver/cuprous oxide multi-element nanocomposite and preparation method of modified electrode | 宁德师范学院 | 2024-02-13 | — | — | CN | disclosed |
| EP-4204089-A1 | CHEMICAL PROBES AND INHIBITORS FOR POLYPEPTIDES OF SARS CORONAVIRUSES | Universität Konstanz (DE) | 2023-07-05 | — | — | EP | disclosed |
| CN-113804738-B | Polyaniline-loaded cuprous oxide sensing electrode and preparation thereof | 宁德师范学院 | 2023-04-25 | — | — | CN | disclosed |
| CN-113804738-A | Polyaniline-loaded cuprous oxide sensing electrode and preparation thereof | 宁德师范学院 | 2021-12-17 | — | — | CN | disclosed |
| CN-113804737-A | Preparation method of polyaniline-loaded silver/cuprous oxide multi-element nano composite material and modified electrode | 宁德师范学院 | 2021-12-17 | — | — | CN | disclosed |
| CN-110514726-B | Fe-PANI/Au modified electrode for sensitive detection of dopamine and uric acid and preparation thereof | 宁德师范学院 | 2021-08-13 | — | — | CN | disclosed |
| CN-110514725-B | Fe-PANI-based dopamine electrochemical sensing electrode and preparation thereof | 宁德师范学院 | 2020-12-11 | — | — | CN | disclosed |
| US-6284036-B1 | PIGMENTING POROUS SINTERED MATERIAL COMPRISING BORIDE, CARBIDE, SILICIDE, NITRIDE OR PHOSPHIDES BY APPLYING SOLUTION OF SOLUBLE PIGMENT DERIVATIVE AND REGENERATING ORGANIC PIGMENT BY HEATING TO DEPOSIT PIGMENT IN PORES | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-09-04 | — | — | US | disclosed |
| EP-0975600-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | Akzo Nobel N.V. (NL) | 2000-02-02 | — | — | EP | disclosed |
| JP-H1135705-A | PRODUCTION OF POLYETHERSULFONE RESIN FILM | SUMITOMO CHEM CO LTD | 1999-02-09 | — | — | JP | disclosed |
| WO-1998047876-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | AKZO NOBEL N.V. (NL) | 1998-10-29 | — | — | WO | disclosed |
| WO-1997004770-A1 | 2-(FLUORENONYL)-CARBAPENEMS, COMPOSITIONS AND METHODS OF USE | MERCK & CO., INC. (US) | 1997-02-13 | — | — | WO | disclosed |
| US-5451579-A | 1-β-methyl-carbapenem, compositions containing same and methods of use | MERCK & CO., INC. (US) | 1995-09-19 | — | — | US | disclosed |
| WO-1995021841-A1 | 1-β-METHYL-CARBAPENEM, COMPOSITIONS CONTAINING SAME AND METHODS OF USE | MERCK & CO., INC. (US) | 1995-08-17 | — | — | WO | disclosed |
| US-4113680-A | Method for preparing 17 α-ester-21-halo pregnanes | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1978-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190002461-A1 | NOVEL POLYMORPH OF RIOCIGUAT AND ITS PROCESS FOR THE PREPARATION | RIOK1, RIOK2, RIOK3 | BRD4 4863/4885BRD2 4867/4885PIK3CD 2442/4885 |
| US-10414766-B2 | Polymorph of Riociguat and its process for the preparation | RIOK2, RIOK1, RIOK3 | BRD4 4877/4885BRD2 4878/4885PIK3CD 2600/4885 |
| US-20130123499-A1 | Method for Purifying a Fused Pyrrolocarbazole Derivative | PYCR1, PGA5, PAICS | BRD4 259/4885BRD2 1258/4885PIK3CD 2407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.