Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 18/20 | 0.62 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.62 |
| ▸ | PTPRC | P08575 | 3/20 | 0.62 |
| ▸ | PTPRB | P23467 | 2/20 | 0.62 |
| ▸ | PTPRE | P23469 | 2/20 | 0.62 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.56 |
| ▸ | PTPRA | P18433 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7534114 | 0.82 | ALDH1A1 (0.47) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL4312414 | 0.77 | PTPN1 (1.00) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL21597600 | 0.73 | FLT3 (0.49) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL7491768 | 0.73 | PTPN1 (0.55) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL7562771 | 0.72 | PTPN1 (0.35) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL27558405 | 0.72 | ALDH1A1 (0.43) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL5837972 | 0.72 | PTPN1 (1.00) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL7537079 | 0.71 | ALDH1A1 (0.47) | POLBKMT2A | |
| SCHEMBL22372483 | 0.69 | PTPN1 (1.00) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL6315134 | 0.69 | PTPN1 (1.00) | PTPN1PTPN2PTPRCPTPRBPTPRE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002506073-A | — | — | 2002-02-26 | — | — | JP | claimed |
| EP-1062218-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2000-12-27 | — | — | EP | claimed |
| WO-1999046268-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 1999-09-16 | — | — | WO | claimed |
| US-20020019412-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2002-02-14 | — | — | US | disclosed |
| EP-1062218-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2000-12-27 | — | — | EP | disclosed |
| WO-1999046268-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 1999-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019412-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | PTPRCAP, PTPRS, PTPRA | PTPN1 7/4885PTPN2 9/4885PTPRC 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.