Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPRB | P23467 | 1/20 | 0.34 |
| ▸ | PTPRE | P23469 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540382 | 0.77 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4EADORA1HPGD | |
| SCHEMBL15199371 | 0.75 | MAPT (0.39) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL8189546 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EADORA1RAD52 | |
| SCHEMBL3500340 | 0.72 | PTPRC (0.58) | ALDH1A1MAPTKDM4EADORA1RAD52 | |
| SCHEMBL7540375 | 0.72 | PTPN1 (0.62) | KMT2APTPRCPTPN2PTPN1PTPRB | |
| SCHEMBL15200410 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL7482154 | 0.67 | ADORA1 (0.37) | ALDH1A1MAPTKDM4EADORA1RAD52 | |
| SCHEMBL644159 | 0.67 | ALDH1A1 (0.73) | ALDH1A1MAPTKDM4EADORA1RAD52 | |
| SCHEMBL11479163 | 0.67 | ALDH1A1 (0.73) | ALDH1A1MAPTKDM4EADORA1RAD52 | |
| SCHEMBL7562771 | 0.67 | PTPN1 (0.35) | KMT2APTPRCPTPN2PTPN1PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1300279-A | Modulators of protein tyrosine phosphatases | NOVO NORDISK AS (DK) | 2001-06-20 | — | — | CN | disclosed |